Inhibits cellular Ca²⁺ uptake and calcium mobilization. Inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis. Anti-inflammatory *pound. Has anti-thrombotic, anti-proliferative and anti-mitogenic effects.Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC₅₀=0.64µM for 12-LO and 1.6µM for 15-LO). Inhibits leukotriene biosynthesis (at higher concentrations) and release of lysosomal enzymes.