藜蘆定/Veratridine
A Na+ channel activator. Does not affect Na+-Ca2+ exchange. Veratridine acts at neurotoxin receptor site 2 and preferentially binds to activated Na+ channels causing persistent activation. It prevents inactivation and shifts activation to more negative potentials. Induces cell death in bovine chromaffin cells.
PRODUCT PROPERTIES
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml)
Long Term Storage: -20°C
Use/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.
Hazard: VERY TOXIC.
MW: 673.8
CAS: 71-62-5
Formula: C36H51NO11
Purity: ≥98%
Appearance: White to yellow solid
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